2. Superantigens, steroid insensitivity and innate immunity in atopic eczema

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Superantigens, steroid insensitivity and innate immunity in atopic eczema.

There is now considerable evidence that colonization or infection with Staphylococcus aureus is an exacerbating factor in atopic dermatitis (AD) (1). Numerous studies have shown that the superantigens produced by staphylococci and streptococci are implicated in the pathogenesis of various inflammatory skin diseases. The skin lesions of patients with AD predominantly contain infiltrating T cells...

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Humoral and cellular immunity in atopic eczema.

Parameters of humoral and cellular immunity were measured in thirty-five patients with atopic eczema. The mean serum IgE level was raised but levels of the other major immunoglobulin classes were normal. Ten per cent of patients failed to respond to tetanus immunization. All patients responded to S. typhi H antigen. Fourteen per cent of patients failed to mount delayed hypersensitivity reaction...

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Soluble interleukin 2 receptor in atopic eczema.

OBJECTIVE To determine whether serum soluble interleukin 2 receptor concentrations are related to disease activity in atopic eczema. DESIGN Single cohort longitudinal study with controls. SETTING Outpatient and general medicine departments in secondary referral centre. PATIENTS Of 15 patients aged 17-57 with severe atopic eczema, all with acute exacerbations of disease, 13 were admitted t...

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Atopic and Non-atopic Eczema.

Atopic dermatitis is a common term used in the medical literature, but according to The Nomenclature Review Committee Of The World Allergy Organization the name which should be used is eczema. Eczema is divided into two subtypes: atopic and non-atopic. These subtypes differ in the level of total immunoglobulin E (IgE) in serum, response to allergens in skin prick tests, and detection of specifi...

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Growth in atopic eczema.

Growth was studied in 68 children aged 2-12 years with atopic eczema. Height SD scores were significantly correlated with the surface area of skin affected by eczema. The mean height of 41 patients with less than 50% of their skin surface affected (group I) was normal (mean SD score -0.11). The 27 children with more than 50% of their skin affected (group II) were significantly shorter (SD score...

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ژورنال

عنوان ژورنال: Acta Dermato-Venereologica

سال: 2005

ISSN: 0001-5555

DOI: 10.1080/03658340510012435